Concepedia

Transporter Polymorphism Effects

Transporter Polymorphism Effects is a pharmacogenetic phenomenon characterized by altered transporter protein function due to genetic variants, leading to interindividual variability in the absorption, distribution, metabolism, and excretion of drugs mediated by membrane transporters.

410

Publications

31.6K

Citations

2.6K

Authors

802

Institutions

Publications per year

2017–2026

40

Parents

Publications

410

Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity <i>in</i> <i>vivo</i>

Sven Hoffmeyer, Oliver Burk, Oliver von Richter et al. · Proceedings of the National Academy of Sciences · 2000 · 2.4K citations

, , +15

Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action

Yan Shu, Steven A. Sheardown, Chaline Brown et al. · Journal of Clinical Investigation · 2007 · 958 citations · Full text

, , +13

The Interaction of Stressful Life Events and a Serotonin Transporter Polymorphism in the Prediction of Episodes of Major Depression

Kenneth S. Kendler, Jonathan W. Kuhn, Jen Vittum et al. · Archives of General Psychiatry · 2005 · 666 citations

, , +17

Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study

Jacques Fellay, Catia Marzolini, E. Rhiannon Meaden et al. · The Lancet · 2002 · 662 citations · Full text

, , +17

Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

Sven Hoffmeyer · Proceedings of the National Academy of Sciences · 2000 · 598 citations

, , +17

1–5 of 410

Authors

2.6K

  1. JB
    Jürgen Brockmöller

    University of Göttingen, Germany

    11 publications · 1.1K citations

    11

    h-index

  2. MV
    Mladen V. Tzvetkov

    University of Göttingen, Germany

    10 publications · 909 citations

    10

    h-index

  3. KM
    Kathleen M. Giacomini

    University of California, San Francisco, United States

    9 publications · 1.9K citations

    9

    h-index

  4. MN
    Mikko Niemi

    University of Helsinki, Finland

    5 publications · 1K citations

    5

    h-index

  5. AH
    Albert Hofman

    Erasmus MC, Netherlands

    5 publications · 500 citations

    5

    h-index

1–5 of 2.6K

Institutions

802

  1. University of California, San Francisco

    San Francisco, United States

    17 h-index

    99 publications

    13.3K citations

  2. University of Göttingen

    Göttingen, Germany

    11 h-index

    62 publications

    6.2K citations

  3. Heidelberg University

    Heidelberg, Germany

    11 h-index

    34 publications

    2.8K citations

  4. University of California, Los Angeles

    Los Angeles, United States

    9 h-index

    18 publications

    580 citations

  5. University of Würzburg

    Würzburg, Germany

    9 h-index

    24 publications

    2.9K citations

  6. University of Bonn

    Bonn, Germany

    9 h-index

    36 publications

    1.4K citations

  7. Akita University

    Akita, Japan

    8 h-index

    38 publications

    3.2K citations

  8. King's College London

    London, United Kingdom

    8 h-index

    21 publications

    1.5K citations

1–8 of 802

Venues

  1. Molecular Psychiatry

    15 publications · 2.1K citations

    15

    h-index

  2. PubMed

    Repository · 15 publications · 867 citations

    13

    h-index

  3. Pharmacogenetics and Genomics

    11 publications · 1.7K citations

    11

    h-index

  4. Neuroscience Letters

    10 publications · 517 citations

    10

    h-index

  5. Biological Psychiatry

    10 publications · 1.3K citations

    10

    h-index

1–5