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Engineered allosteric activation of kinases in living cells

Andrei V. Karginov, Feng Ding, Pradeep Kota, Nikolay V. Dokholyan, Klaus M. Hahn

Nature Biotechnology · 2010 · 208 citations · 26 references

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References

26

FAK integrates growth-factor and integrin signals to promote cell migration

David J. Sieg, Christof R. Hauck, Duško Ilić et al. · Nature Cell Biology · 2000 · 1.2K citations · Full text

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Autophosphorylation of the Focal Adhesion Kinase, ppl25<sup>FAK</sup>, Directs SH2-Dependent Binding of pp60<i><sup>src</sup></i>

Michael D. Schaller, Jeffrey D. Hildebrand, John D. Shannon et al. · Molecular and Cellular Biology · 1994 · 1.1K citations · Full text

, , +17

A chemical switch for inhibitor-sensitive alleles of any protein kinase

Anthony C. Bishop, Jeffrey A. Ubersax, Dejah T. Petsch et al. · Nature · 2000 · 1.1K citations

, , +15

A Rapid, Reversible, and Tunable Method to Regulate Protein Function in Living Cells Using Synthetic Small Molecules

Laura A. Banaszynski, Ling-chun Chen, Lystranne A. Maynard-Smith et al. · Cell · 2006 · 958 citations · Full text

, , +10

Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src.

Michael D. Schaller, Jeffrey D. Hildebrand, John D. Shannon et al. · Molecular and Cellular Biology · 1994 · 868 citations · Full text

, , +17