David J. Sieg

FAK integrates growth-factor and integrin signals to promote cell migration

David J. Sieg, Christof R. Hauck, Duško Ilić et al. · Nature Cell Biology · 2000 · 1.2K citations · Full text

Developmental Biology, Signal Transduction, Cell-matrix Interaction +8

Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration

David J. Sieg, Christof R. Hauck, David D. Schlaepfer · Journal of Cell Science · 1999 · 676 citations

Focal adhesion kinase suppresses Rho activity to promote focal adhesion turnover

Xiang-Dong Ren, William B. Kiosses, David J. Sieg et al. · Journal of Cell Science · 2000 · 458 citations

Cell Adhesion, Cytoskeleton, Focal Adhesion Turnover +16

Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration

David J. Sieg · The EMBO Journal · 1998 · 333 citations · Full text

Signal Transduction, Fibronectin-stimulated Signaling Events, Signaling Pathway +10

Inhibition of focal adhesion kinase expression or activity disrupts epidermal growth factor-stimulated signaling promoting the migration of invasive human carcinoma cells.

Christof R. Hauck, David J. Sieg, Datsun A. Hsia et al. · PubMed · 2001 · 250 citations

Cell Adhesion, Pathology, Cell Culture +16