Concepedia

Factor VIIa inhibitors: A prodrug strategy to improve oral bioavailability

Jennifer R. Riggs, Aleksandr Kolesnikov, John E. Hendrix, Wendy B. Young, William D. Shrader, Dange Vijaykumar, Robin Stephens, Liang Liu, Lin Pan, Joyce Mordenti,

Bioorganic & Medicinal Chemistry Letters · 2006 · 27 citations · 12 references

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12

Fast Calculation of Molecular Polar Surface Area as a Sum of Fragment-Based Contributions and Its Application to the Prediction of Drug Transport Properties

Peter Ertl, Bernhard Rohde, Paul M. Selzer · Journal of Medicinal Chemistry · 2000 · 3K citations

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Convenient Method for the ortho-Formylation of Phenols.

Nini U. Hofsløkken, Lars Skattebøl, Fredrik Johansson et al. · Acta chemica Scandinavica/Acta chemica Scandinavica. B, Organic chemistry and biochemistry/Acta chemica Scandinavica. A, Physical and inorganic chemistry/Acta chemica Scandinavica. Series B. Organic chemistry and biochemistry/Acta chemica Scandinavica. Series A, Physical and inorganic chemistry · 1999 · 201 citations · Full text

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Absorption, Distribution, Metabolism, and Excretion of Ximelagatran, an Oral Direct Thrombin Inhibitor, in Rats, Dogs, and Humans

Ulf G. Eriksson, Ulf Bredberg, Kurt‐Jürgen Hoffmann et al. · Drug Metabolism and Disposition · 2003 · 155 citations

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Development of Serine Protease Inhibitors Displaying a Multicentered Short (<2.3 Å) Hydrogen Bond Binding Mode:  Inhibitors of Urokinase-Type Plasminogen Activator and Factor Xa

Erik Verner, B.A. Katz, Jeffrey R. Spencer et al. · Journal of Medicinal Chemistry · 2001 · 124 citations · Full text

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Prodrugs for Amidines:  Synthesis and Anti-<i>Pneumocystis carinii</i> Activity of Carbamates of 2,5-Bis(4-amidinophenyl)furan

Syed M. Rahmathullah, James Edwin Hall, Brendan C. Bender et al. · Journal of Medicinal Chemistry · 1999 · 95 citations

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