Concepedia

Oral Bioavailability

Oral Bioavailability is the fraction of an orally administered drug that reaches the systemic circulation in its unchanged form, distinguishing it from other routes of administration by accounting for both incomplete absorption and presystemic metabolism specific to the gastrointestinal tract and hepatic first-pass effect.

4.1K

Publications

223.9K

Citations

16.5K

Authors

3.1K

Institutions

Publications per year

2017–2026

744

Parents

Children

Publications

4.1K

Molecular Properties That Influence the Oral Bioavailability of Drug Candidates

Daniel F. Veber, Stephen R. Johnson, Hung‐Yuan Cheng et al. · Journal of Medicinal Chemistry · 2002 · 8.1K citations

, , +15

A comparison of the Two One-Sided Tests Procedure and the Power Approach for assessing the equivalence of average bioavailability

Donald J. Schuirmann · Journal of Pharmacokinetics and Biopharmaceutics · 1987 · 2.6K citations · Full text

, , +10

Influence of Piperine on the Pharmacokinetics of Curcumin in Animals and Human Volunteers

Guido Shoba, David C. Joy, Thangam Joseph et al. · Planta Medica · 1998 · 1.9K citations

, , +13

HIGH ABSORPTION BUT VERY LOW BIOAVAILABILITY OF ORAL RESVERATROL IN HUMANS

Thomas Walle, Faye Hsieh, Mark H. DeLegge et al. · Drug Metabolism and Disposition · 2004 · 1.8K citations

, , +15

The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors.

Richard B. Kim, Martin F. Fromm, Christoph Wandel et al. · Journal of Clinical Investigation · 1998 · 1.1K citations · Full text

, , +17

1–5 of 4.1K

Authors

16.5K

  1. JD
    Jennifer Dressman

    Goethe University Frankfurt, Germany

    46 publications · 3.7K citations

    30

    h-index

  2. VP
    Vinod P. Shah

    Center for Drug Evaluation and Research, United States

    40 publications · 2.3K citations

    27

    h-index

  3. GL
    Gordon L. Amidon

    University of Michigan, United States

    26 publications · 2.3K citations

    24

    h-index

  4. DB
    D.M. Barends

    National Institute for Public Health and the Environment, Netherlands

    26 publications · 2K citations

    22

    h-index

  5. PL
    Peter Langguth

    Johannes Gutenberg University Mainz, Germany

    24 publications · 1.2K citations

    19

    h-index

1–5 of 16.5K

Institutions

3.1K

  1. University of Michigan

    Ann Arbor, United States

    33 h-index

    139 publications

    13.5K citations

  2. Goethe University Frankfurt

    Frankfurt am Main, Germany

    33 h-index

    93 publications

    5.7K citations

  3. Shenyang Pharmaceutical University

    Shenyang, China

    31 h-index

    277 publications

    13.1K citations

  4. Rutgers, The State University of New Jersey

    New Brunswick, United States

    29 h-index

    116 publications

    9.6K citations

  5. National Institute for Public Health and the Environment

    De Bilt, The Netherlands

    28 h-index

    57 publications

    4K citations

  6. Pfizer (United States)

    New York, United States

    25 h-index

    143 publications

    11.1K citations

  7. China Pharmaceutical University

    Nanjing, China

    25 h-index

    215 publications

    8.9K citations

  8. Novartis (Switzerland)

    Basel, Switzerland

    23 h-index

    119 publications

    6.6K citations

1–8 of 3.1K

Venues

  1. Clinical Pharmacology & Therapeutics

    CPT · 104 publications · 9K citations

    54

    h-index

  2. International Journal of Pharmaceutics

    158 publications · 9.3K citations

    51

    h-index

  3. Journal of Pharmaceutical Sciences

    185 publications · 9K citations

    50

    h-index

  4. PubMed

    Repository · 276 publications · 9.1K citations

    48

    h-index

  5. The Journal of Clinical Pharmacology

    111 publications · 7K citations

    47

    h-index

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