Ulf Bredberg

The Direct Thrombin Inhibitor Melagatran and Its Oral Prodrug H 376/95: Intestinal Absorption Properties, Biochemical and Pharmacodynamic Effects

David Gustafsson, Jan-Erik Nyström, Stefan Carlsson et al. · Thrombosis Research · 2001 · 302 citations

Pharmaceutical Science, Biochemistry, Medicine +5

Structure−Brain Exposure Relationships in Rat and Human Using a Novel Data Set of Unbound Drug Concentrations in Brain Interstitial and Cerebrospinal Fluids

Markus Fridén, Susanne Winiwarter, Gunilla Jerndal et al. · Journal of Medicinal Chemistry · 2009 · 224 citations

Structure−brain Exposure Relationships, Experimental Pharmacology, Unbound Brain Exposure +19

In Vitro Methods for Estimating Unbound Drug Concentrations in the Brain Interstitial and Intracellular Fluids

Markus Fridén, Anubha Gupta, Madeleine Antonsson et al. · Drug Metabolism and Disposition · 2007 · 199 citations

Measurement of Unbound Drug Exposure in Brain: Modeling of pH Partitioning Explains Diverging Results between the Brain Slice and Brain Homogenate Methods

Markus Fridén, Fredrik Bergström, Hong Wan et al. · Drug Metabolism and Disposition · 2010 · 183 citations

Absorption, Distribution, Metabolism, and Excretion of Ximelagatran, an Oral Direct Thrombin Inhibitor, in Rats, Dogs, and Humans

Ulf G. Eriksson, Ulf Bredberg, Kurt‐Jürgen Hoffmann et al. · Drug Metabolism and Disposition · 2003 · 154 citations