William D. Shrader

Initial experience in the treatment of inherited mitochondrial disease with EPI-743

Gregory M. Enns, Stephen L. Kinsman, Susan Perlman et al. · Molecular Genetics and Metabolism · 2011 · 196 citations · Full text

Mitochondrial Dysfunction, Genetics, Genetic Epidemiology +22

EPI-743 reverses the progression of the pediatric mitochondrial disease—Genetically defined Leigh Syndrome

Diego Martinelli, Michela Catteruccia, Fiorella Piemonte et al. · Molecular Genetics and Metabolism · 2012 · 184 citations

Mitochondrial Function, Genetic Disorder, Genetics +9

Vitamin E hydroquinone is an endogenous regulator of ferroptosis via redox control of 15-lipoxygenase

A. Scott Hinman, Charles R. Holst, Joey C. Latham et al. · PLoS ONE · 2018 · 170 citations · Full text

Development of Serine Protease Inhibitors Displaying a Multicentered Short (<2.3 Å) Hydrogen Bond Binding Mode:  Inhibitors of Urokinase-Type Plasminogen Activator and Factor Xa

Erik Verner, B.A. Katz, Jeffrey R. Spencer et al. · Journal of Medicinal Chemistry · 2001 · 124 citations · Full text

Drug Target, Bioorganic Chemistry, Serine Protease Inhibitors +19

Substrate assistance in the mechanism of family 18 chitinases: theoretical studies of potential intermediates and inhibitors 1 1Edited by B. Honig

Ken A. Brameld, William D. Shrader, Barbara Imperiali et al. · Journal of Molecular Biology · 1998 · 111 citations

Bioorganic Chemistry, Biochemistry, B. Honig +8