Ken A. Brameld

Prolonged and tunable residence time using reversible covalent kinase inhibitors

J. Michael Bradshaw, Jesse M. McFarland, Ville O. Paavilainen et al. · Nature Chemical Biology · 2015 · 422 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +5

Substrate assistance in the mechanism of family 18 chitinases: theoretical studies of potential intermediates and inhibitors 1 1Edited by B. Honig

Ken A. Brameld, William D. Shrader, Barbara Imperiali et al. · Journal of Molecular Biology · 1998 · 111 citations

Bioorganic Chemistry, Biochemistry, B. Honig +8

The role of enzyme distortion in the single displacement mechanism of family 19 chitinases

Ken A. Brameld, William A. Goddard · Proceedings of the National Academy of Sciences · 1998 · 108 citations · Full text

Preclinical Efficacy and Anti-Inflammatory Mechanisms of Action of the Bruton Tyrosine Kinase Inhibitor Rilzabrutinib for Immune-Mediated Disease

Claire L. Langrish, J. Michael Bradshaw, Michelle Francesco et al. · The Journal of Immunology · 2021 · 108 citations · Full text

The chitinase PfCHT1 from the human malaria parasite <i>Plasmodium falciparum</i> lacks proenzyme and chitin-binding domains and displays unique substrate preferences

Joseph M. Vinetz, Sanat K. DAVÉ, Charles A. Specht et al. · Proceedings of the National Academy of Sciences · 1999 · 107 citations · Full text