Concepedia

Cytotoxic effects of 109 reference compounds on rat H4IIE and human HepG2 hepatocytes. III: Mechanistic assays on oxygen consumption with MitoXpress and NAD(P)H production with Alamar Blue™

W.G.E.J. Schoonen, Joe C.R. Stevenson, Walter M.A. Westerink, G. Jean Horbach

Toxicology in Vitro · 2012 · 26 citations · 55 references

DOI

Concepts

References

55

Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells

Min Wu, Andy Neilson, Amy L. Swift et al. · American Journal of Physiology-Cell Physiology · 2006 · 920 citations

, , +17

Circumventing the Crabtree Effect: Replacing Media Glucose with Galactose Increases Susceptibility of HepG2 Cells to Mitochondrial Toxicants

Lisa D. Marroquin, James T. Hynes, James A. Dykens et al. · Toxicological Sciences · 2007 · 639 citations

, , +17

High concordance of drug-induced human hepatotoxicity with in vitro cytotoxicity measured in a novel cell-based model using high content screening

Peter J. O’Brien, William Irwin, Dolores Diaz et al. · Archives of Toxicology · 2006 · 609 citations

, , +16

Comparison of alamar blue and MTT assays for high through-put screening

Roslida Abd Hamid, Yakov Rotshteyn, Leyana Rabadi et al. · Toxicology in Vitro · 2004 · 568 citations

, , +7

Cytochrome P450 enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells

Walter M.A. Westerink, W.G.E.J. Schoonen · Toxicology in Vitro · 2007 · 525 citations

, , +16