Concepedia

Hepatocellular Toxicity

Hepatocellular Toxicity is a form of cellular toxicity characterized by the selective impairment or damage of hepatocytes, the primary functional cells of the liver, resulting from exposure to toxic agents that disrupt hepatic physiological functions.

2K

Publications

90.8K

Citations

8.2K

Authors

1.9K

Institutions

Publications per year

2017–2026

296

Parents

Publications

2K

COMPARISON OF PRIMARY HUMAN HEPATOCYTES AND HEPATOMA CELL LINE HEPG2 WITH REGARD TO THEIR BIOTRANSFORMATION PROPERTIES

Stefan Wilkening, Frank Stahl, Augustinus Bader · Drug Metabolism and Disposition · 2003 · 771 citations

, , +17

Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease

Catherine C. Bell, Delilah Hendriks, Sabrina Moro et al. · Scientific Reports · 2016 · 708 citations · Full text

, , +17

Outcome and prognostic markers in severe drug‐induced liver disease†

Einar S. Björnsson, Rolf Olsson · Hepatology · 2005 · 598 citations · Full text

, , +17

Bleb Formation in Hepatocytes During Drug Metabolism Is Caused by Disturbances in Thiol and Calcium Ion Homeostasis

Sarah A. Jewell, Giorgio Bellomo, Hjördis Thor et al. · Science · 1982 · 555 citations

, , +16

Murine hepatocyte apoptosis induced in vitro and in vivo by TNF- <i>alpha</i> requires transcriptional arrest.

Marcel Leist, Florian Gantner, I Bohlinger et al. · The Journal of Immunology · 1994 · 495 citations · Full text

, , +17

1–5 of 2K

Authors

8.2K

  1. HM
    Harihara M. Mehendale

    University of Louisiana at Monroe, United States

    14 publications · 614 citations

    14

    h-index

  2. SK
    Stephan Krähenbühl

    University Hospital of Basel, Switzerland

    12 publications · 700 citations

    12

    h-index

  3. RJ
    Raúl J. Andrade

    Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Spain

    12 publications · 1.3K citations

    11

    h-index

  4. KN
    Kasuke Nagano

    Japan Industrial Safety and Health Association, Japan

    10 publications · 305 citations

    10

    h-index

  5. JM
    Jerrold M. Ward

    National Cancer Institute, United States

    11 publications · 458 citations

    10

    h-index

1–5 of 8.2K

Institutions

1.9K

  1. Research Triangle Park Foundation

    Durham, United States

    24 h-index

    106 publications

    5.6K citations

  2. Inserm

    Paris, France

    22 h-index

    128 publications

    5.5K citations

  3. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    21 h-index

    73 publications

    3.8K citations

  4. University of Toronto

    Toronto, Canada

    21 h-index

    68 publications

    3.9K citations

  5. National Institutes of Health

    Bethesda, United States

    20 h-index

    61 publications

    2.8K citations

  6. National Cancer Institute

    Bethesda, United States

    18 h-index

    49 publications

    3K citations

  7. Environmental Protection Agency

    Washington, United States

    18 h-index

    61 publications

    2.9K citations

  8. Chinese Academy of Sciences

    Beijing, China

    16 h-index

    52 publications

    2.4K citations

1–8 of 1.9K

Venues

  1. PubMed

    Repository · 161 publications · 7.2K citations

    45

    h-index

  2. Toxicology and Applied Pharmacology

    TAAP · 88 publications · 3.9K citations

    37

    h-index

  3. Toxicological Sciences

    58 publications · 3.9K citations

    35

    h-index

  4. Toxicology in Vitro

    65 publications · 2.5K citations

    30

    h-index

  5. Carcinogenesis

    47 publications · 2.2K citations

    28

    h-index

1–5