G. Jean Horbach

DuoBody-CD3xCD20 induces potent T-cell-mediated killing of malignant B cells in preclinical models and provides opportunities for subcutaneous dosing

Patrick Engelberts, Ida H. Hiemstra, Bart de Jong et al. · EBioMedicine · 2020 · 159 citations · Full text

Evaluation of the Vitotox™ and RadarScreen assays for the rapid assessment of genotoxicity in the early research phase of drug development

Walter M.A. Westerink, Joe C.R. Stevenson, Annick Lauwers et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2009 · 74 citations

Preclinical Drug Evaluation, Radarscreen Assays, Drug Discovery +9

The development of RAD51C, Cystatin A, p53 and Nrf2 luciferase-reporter assays in metabolically competent HepG2 cells for the assessment of mechanism-based genotoxicity and of oxidative stress in the early research phase of drug development

Walter M.A. Westerink, Joe C.R. Stevenson, G. Jean Horbach et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2009 · 73 citations

Reductive Stress, Medicine, Lipid Peroxidation +8

Development and validation of a high-content screening in vitro micronucleus assay in CHO-k1 and HepG2 cells

Walter M.A. Westerink, Tom J.J. Schirris, G. Jean Horbach et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2011 · 67 citations

Medicine, Hepg2 Cells, Bioanalysis +11

Development of human cytochrome P450-expressing cell lines: application in mutagenicity testing of ochratoxin A.

Els M. de Groene, Ine Hassing, Maarten J. Blom et al. · PubMed · 1996 · 62 citations

Immunotoxicology, Pathology, Redox Biology +17