Tom J.J. Schirris

Statin-Induced Myopathy Is Associated with Mitochondrial Complex III Inhibition

Tom J.J. Schirris, G. Herma Renkema, Tina Ritschel et al. · Cell Metabolism · 2015 · 222 citations · Full text

Mitochondrial Myopathy, Mitochondrial Function, Mitochondrial Dynamic +3

Flow stimulates drug transport in a human kidney proximal tubule-on-a-chip independent of primary cilia

Jelle Vriend, Janny G.P. Peters, Tom T.G. Nieskens et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 2019 · 89 citations · Full text

Development and validation of a high-content screening in vitro micronucleus assay in CHO-k1 and HepG2 cells

Walter M.A. Westerink, Tom J.J. Schirris, G. Jean Horbach et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2011 · 67 citations

Medicine, Hepg2 Cells, Bioanalysis +11

Safety of drug use in patients with a primary mitochondrial disease: An international Delphi‐based consensus

Maaike C. de Vries, David A. Brown, Mitchell E. Allen et al. · Journal of Inherited Metabolic Disease · 2020 · 64 citations · Full text

Drug Safety, Mitochondrial Function, Pharmacology +14

Mitoenergetic Dysfunction Triggers a Rapid Compensatory Increase in Steady-State Glucose Flux

Dania C. Liemburg-Apers, Tom J.J. Schirris, Frans G. M. Rüssel et al. · Biophysical Journal · 2015 · 56 citations · Full text

Energy Homeostasis, Rapid Compensatory Increase, Diabetes +10