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The development of RAD51C, Cystatin A, p53 and Nrf2 luciferase-reporter assays in metabolically competent HepG2 cells for the assessment of mechanism-based genotoxicity and of oxidative stress in the early research phase of drug development

Reductive StressMedicineLipid PeroxidationHepatotoxicityCystatin AReactive Oxygen SpeciePharmacologyCell BiologyRedox BiologyCompetent Hepg2 CellsOxidative Stress