Concepedia

Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB

Hui-Kuan Lin, Guocan Wang, Zhenbang Chen, Julie Teruya‐Feldstein, Yan Liu, Chia‐Hsin Chan, Wei-Lei Yang, Hediye Erdjument‐Bromage, Keiichi I. Nakayama, Stephen D. Nimer,

Nature Cell Biology · 2009 · 236 citations · 37 references

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References

37

Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor

Anne Brunet, Azad Bonni, Michael J. Zigmond et al. · Cell · 1999 · 6.6K citations · Full text

, , +13

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

Ken Inoki, Yong Li, Tianquan Zhu et al. · Nature Cell Biology · 2002 · 3.1K citations

, , +6

Identification of the Tuberous Sclerosis Complex-2 Tumor Suppressor Gene Product Tuberin as a Target of the Phosphoinositide 3-Kinase/Akt Pathway

Brendan D. Manning, Andrew R. Tee, M. Nicole Logsdon et al. · Molecular Cell · 2002 · 1.6K citations · Full text

, , +12

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

Andrea C. Carrano, Esther Eytan, Avram Hershko et al. · Nature Cell Biology · 1999 · 1.5K citations

, , +12

Structure of the Cul1–Rbx1–Skp1–F boxSkp2 SCF ubiquitin ligase complex

Ning Zheng, Brenda A. Schulman, Langzhou Song et al. · Nature · 2002 · 1.5K citations

, , +9