Skp2 E3 Ligase Integrates ATM Activation and Homologous Recombination Repair by Ubiquitinating NBS1

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

Andrea C. Carrano, Esther Eytan, Avram Hershko et al. · Nature Cell Biology · 1999 · 1.5K citations

Ubiquitin-mediated Degradation, Signal Transduction, Cell Regulation +9

ATM Activation by DNA Double-Strand Breaks Through the Mre11-Rad50-Nbs1 Complex

Ji‐Hoon Lee, Tanya T. Paull · Science · 2005 · 1.4K citations

Chromatin, Genome Instability, Dna Damage +14

The hMre11/hRad50 Protein Complex and Nijmegen Breakage Syndrome: Linkage of Double-Strand Break Repair to the Cellular DNA Damage Response

James P. Carney, Richard S. Maser, Heidi Olivares et al. · Cell · 1998 · 1.2K citations · Full text

Chromatin, Genome Instability, Double-strand Break Repair +11

Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage

Jacob Falck, Julia Coates, Stephen P. Jackson · Nature · 2005 · 1.2K citations

Chromatin, Genome Instability, Conserved Modes +8

RNF8 Ubiquitylates Histones at DNA Double-Strand Breaks and Promotes Assembly of Repair Proteins

Niels Mailand, Simon Bekker‐Jensen, Helene Faustrup et al. · Cell · 2007 · 1.1K citations · Full text

Chromatin, Genome Instability, Repair Proteins +8