Concepedia

Dna Ligase Function

DNA Ligase Function is a molecular biological process that belongs to the class of enzymatic activities involved in DNA repair, specifically defined by its role in catalyzing the formation of phosphodiester bonds to seal nicks in double-stranded DNA during the final step of double-strand break repair pathways.

984

Publications

67.3K

Citations

3.3K

Authors

857

Institutions

Publications per year

2017–2026

100

Parents

Publications

984

Genetic disease detection and DNA amplification using cloned thermostable ligase.

Francis Barany · Proceedings of the National Academy of Sciences · 1991 · 809 citations

, , +17

PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways

Minli Wang, Wei‐Zhong Wu, Wenqi Wu et al. · Nucleic Acids Research · 2006 · 800 citations · Full text

, , +17

Poly(ADP-Ribose) in the Cellular Response to DNA Damage

Nathan A. Berger · Radiation Research · 1985 · 775 citations

, , +17

Biochemical Method for Inserting New Genetic Information into DNA of Simian Virus 40: Circular SV40 DNA Molecules Containing Lambda Phage Genes and the Galactose Operon of <i>Escherichia coli</i>

David A. Jackson, Robert H. Symons, Paul Berg · Proceedings of the National Academy of Sciences · 1972 · 762 citations · Full text

, , +17

Poly(ADP-ribose) Polymerase-2 (PARP-2) Is Required for Efficient Base Excision DNA Repair in Association with PARP-1 and XRCC1

Valérie Schreiber, Jean‐Christophe Amé, Pascal Dollé et al. · Journal of Biological Chemistry · 2002 · 705 citations · Full text

, , +17

1–5 of 984

Authors

3.3K

  1. AE
    Alan E. Tomkinson

    University of Maryland, Baltimore, United States

    47 publications · 4.6K citations

    33

    h-index

  2. SS
    Stewart Shuman

    Kettering University, United States

    41 publications · 2.3K citations

    28

    h-index

  3. TL
    Tomas Lindahl

    Linköping University, Sweden

    22 publications · 2.5K citations

    21

    h-index

  4. RA
    Robert A. Bambara

    University of Rochester, United States

    17 publications · 1.3K citations

    16

    h-index

  5. AJ
    Aidan J. Doherty

    University of Sussex, United Kingdom

    16 publications · 1.9K citations

    16

    h-index

1–5 of 3.3K

Institutions

857

  1. Kettering University

    Flint, United States

    31 h-index

    105 publications

    5.1K citations

  2. University of Sussex

    Brighton, United Kingdom

    26 h-index

    101 publications

    14.3K citations

  3. National Institutes of Health

    Bethesda, United States

    24 h-index

    88 publications

    6.7K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    23 h-index

    99 publications

    13K citations

  5. Istituto di Genetica Molecolare

    Pavia, Italy

    22 h-index

    118 publications

    4.2K citations

  6. University of Maryland, Baltimore

    Baltimore, United States

    22 h-index

    87 publications

    7.4K citations

  7. University of Rochester

    Rochester, United States

    20 h-index

    63 publications

    4.2K citations

  8. Memorial Sloan Kettering Cancer Center

    New York, United States

    19 h-index

    53 publications

    6.2K citations

1–8 of 857

Venues

  1. Journal of Biological Chemistry

    JBC · 130 publications · 10.7K citations

    60

    h-index

  2. Nucleic Acids Research

    122 publications · 7.6K citations

    49

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 66 publications · 7.4K citations

    43

    h-index

  4. Molecular and Cellular Biology

    MCB · 32 publications · 3.8K citations

    30

    h-index

  5. Biochemistry

    35 publications · 1.6K citations

    26

    h-index

1–5