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The design and synthesis of diaryl ether second generation HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) with enhanced potency versus key clinical mutations

Medicinal ChemistryMedicineNatural SciencesAntiviral Drug DevelopmentAntiviral TherapyMolecular BiologyResistance Mutation (Virology)Key Clinical MutationsHivAntiviral DrugPharmacologyAntiviral CompoundEnhanced PotencyDrug DiscoveryDrug Resistance