Yuexia Liang

Discovery of 3-{5-[(6-Amino-1<i>H</i>-pyrazolo[3,4-<i>b</i>]pyridine-3-yl)methoxy]-2-chlorophenoxy}-5-chlorobenzonitrile (MK-4965): A Potent, Orally Bioavailable HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitor with Improved Potency against Key Mutant Viruses

Thomas J. Tucker, John T. Sisko, Robert M. Tynebor et al. · Journal of Medicinal Chemistry · 2008 · 133 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Ginsenoside Re reduces Aβ production by activating PPARγ to inhibit BACE1 in N2a/APP695 cells

Guoqiong Cao, Ping Su, Shuai Zhang et al. · European Journal of Pharmacology · 2016 · 92 citations

Life Sciences, Cell Biology, Neuroscience +7

The design and synthesis of diaryl ether second generation HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) with enhanced potency versus key clinical mutations

Thomas J. Tucker, Sandeep Saggar, John T. Sisko et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 61 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Characterisation of the absorption, distribution, metabolism, excretion and mass balance of doravirine, a non-nucleoside reverse transcriptase inhibitor in humans

Rosa I. Sánchez, Kerry L. Fillgrove, Ka Lai Yee et al. · Xenobiotica · 2018 · 59 citations

Pharmacy, Clinical Pharmacokinetics, Pharmacology +17

In Vitro Assessment of Drug-Drug Interaction Potential of Boceprevir Associated with Drug Metabolizing Enzymes and Transporters

Xiaoyan Chu, Xiaoxin Cai, Donghui Cui et al. · Drug Metabolism and Disposition · 2013 · 57 citations

Medicine, Pharmacokinetics, Pharmacology +17