Ming‐Tain Lai

Photoactivated γ-secretase inhibitors directed to the active site covalently label presenilin 1

Yue‐Ming Li, Min Xu, Ming‐Tain Lai et al. · Nature · 2000 · 869 citations

Life Sciences, Biochemistry, Molecular Biology +14

Presenilin 1 is linked with γ-secretase activity in the detergent solubilized state

Yue‐Ming Li, Ming‐Tain Lai, Min Xu et al. · Proceedings of the National Academy of Sciences · 2000 · 535 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Structure-Based Design of Potent and Selective Cell-Permeable Inhibitors of Human β-Secretase (BACE-1)

Shawn J. Stachel, Craig A. Coburn, Thomas G. Steele et al. · Journal of Medicinal Chemistry · 2004 · 277 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Presenilin-1 and Presenilin-2 Exhibit Distinct yet Overlapping γ-Secretase Activities

Ming‐Tain Lai, Elizabeth Chen, Ming‐Chih Crouthamel et al. · Journal of Biological Chemistry · 2003 · 169 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +10

Doravirine versus ritonavir-boosted darunavir in antiretroviral-naive adults with HIV-1 (DRIVE-FORWARD): 48-week results of a randomised, double-blind, phase 3, non-inferiority trial

Jean‐Michel Molina, Kathleen Squires, Paul E. Sax et al. · The Lancet HIV · 2018 · 145 citations

Pharmacy, Infectious Diseases, Pharmacotherapy +10