Activation of RalA is critical for Ras-induced tumorigenesis of human cells

ras oncogenes in human cancer: a review.

Joyce Bos · PubMed · 1989 · 5.1K citations

Ras Gene Mutations, Tumor Biology, Ras Oncogenes +15

Creation of human tumour cells with defined genetic elements

William C. Hahn, Christopher M. Counter, Ante S. Lundberg et al. · Nature · 1999 · 2.3K citations

Tumor Biology, Human Cell, Tumor Heterogeneity +6

Stable suppression of tumorigenicity by virus-mediated RNA interference

Thijn R. Brummelkamp, René Bernards, Reuven Agami · Cancer Cell · 2002 · 1.1K citations · Full text

Stable Suppression, Rna Biology, Small Rna +4

Direct control of the Forkhead transcription factor AFX by protein kinase B

Geert J.P.L. Kops, Nancy D. de Ruiter, Alida M.M. de Vries-Smits et al. · Nature · 1999 · 1.1K citations

Transcriptional Regulation, Signal Transduction, Signaling Pathway +11

Role of Phosphoinositide 3-OH Kinase in Cell Transformation and Control of the Actin Cytoskeleton by Ras

Pablo Rodriguez‐Viciana, Patricia H. Warne, Asim Khwaja et al. · Cell · 1997 · 1.1K citations · Full text

Cell Physiology, Signal Transduction, Phosphoinositide 3-Oh Kinase +12