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Role of Phosphoinositide 3-OH Kinase in Cell Transformation and Control of the Actin Cytoskeleton by Ras

Pablo Rodriguez‐Viciana, Patricia H. Warne, Asim Khwaja, Barbara Marte, Darryl Pappin, Pamela Das, Michael D. Waterfield, Anne J. Ridley, Julian Downward

Cell · 1997 · 1.1K citations · 35 references

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35

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

Anne J. Ridley, Alan Hall · Cell · 1992 · 4.5K citations

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The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

Anne J. Ridley, Hugh F. Paterson, Caroline L. Johnston et al. · Cell · 1992 · 3.7K citations

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A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002).

Chris J. Vlahos, William F. Matter, K. Y. Hui et al. · Journal of Biological Chemistry · 1994 · 3.3K citations · Full text

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Phosphatidylinositol-3-OH kinase direct target of Ras

Pablo Rodriguez‐Viciana, Patricia H. Warne, Ritu Dhand et al. · Nature · 1994 · 1.9K citations

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An essential role for Rac in Ras transformation

Rongguo Qiu, Jing Chen, David H. Kirn et al. · Nature · 1995 · 885 citations

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