Concepedia

Actin Filaments

Actin Filaments is a major class of cytoskeletal protein filament in eukaryotic cells, consisting of dynamic, polarized polymers of globular actin subunits assembled into thin (∼7 nm diameter), two-stranded helical fibers that underlie cell shape, cortical structure, and actomyosin-based motility and contractility.

24.2K

Publications

1.8M

Citations

60.5K

Authors

5.8K

Institutions

Publications per year

2017–2026

2.8K

Variants

F-actinMicrofilaments

Parents

Children

Publications

24.2K

The Regulation of Rabbit Skeletal Muscle Contraction

James A. Spudich, Susan Watt · Journal of Biological Chemistry · 1971 · 4.5K citations · Full text

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The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

Anne J. Ridley, Alan Hall · Cell · 1992 · 4.5K citations

, , +17

Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

Catherine D. Nobes, Alan Hall · Cell · 1995 · 4.4K citations · Full text

, , +16

Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion

Tony Yeung, Penelope C. Georges, Lisa A. Flanagan et al. · Cell Motility and the Cytoskeleton · 2004 · 2.3K citations

, , +17

Lifeact: a versatile marker to visualize F-actin

Julia Riedl, Álvaro H. Crevenna, Kai Kessenbrock et al. · Nature Methods · 2008 · 2.3K citations · Full text

, , +9

1–5 of 24.2K

Authors

60.5K

  1. TD
    Thomas D. Pollard

    Yale University, United States

    188 publications · 29.4K citations

    95

    h-index

  2. JH
    John H. Hartwig

    Brigham and Women's Hospital, United States

    103 publications · 15.4K citations

    68

    h-index

  3. TP
    Thomas P. Stossel

    Harvard University, United States

    82 publications · 14.6K citations

    62

    h-index

  4. JA
    John A. Cooper

    Washington University in St. Louis, United States

    89 publications · 10.6K citations

    59

    h-index

  5. PA
    Paul A. Janmey

    University of Pennsylvania, United States

    96 publications · 14.9K citations

    58

    h-index

1–5 of 60.5K

Institutions

5.8K

  1. Harvard University

    Cambridge, United States

    165 h-index

    2.1K publications

    286K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    139 h-index

    952 publications

    183.2K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    131 h-index

    3.4K publications

    262.4K citations

  4. University of Pennsylvania

    Philadelphia, United States

    126 h-index

    1.7K publications

    186.5K citations

  5. Yale University

    New Haven, United States

    122 h-index

    1.2K publications

    145.4K citations

  6. National Institutes of Health

    Bethesda, United States

    113 h-index

    1.5K publications

    146.9K citations

  7. Johns Hopkins University

    Baltimore, United States

    112 h-index

    1.1K publications

    121.3K citations

  8. University of California, San Francisco

    San Francisco, United States

    106 h-index

    766 publications

    103.9K citations

1–8 of 5.8K

Venues

  1. The Journal of Cell Biology

    JCB · 1.6K publications · 246.5K citations

    248

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 928 publications · 109.2K citations

    174

    h-index

  3. Journal of Biological Chemistry

    JBC · 1.6K publications · 142.2K citations

    169

    h-index

  4. Journal of Cell Science

    962 publications · 76.7K citations

    133

    h-index

  5. Nature

    266 publications · 60.2K citations

    131

    h-index

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