Julian Downward

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

Marco Gerlinger, Andrew J. Rowan, Stuart Horswell et al. · New England Journal of Medicine · 2012 · 7.6K citations · Full text

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

A Ullrich, Lisa M. Coussens, Joel S. Hayflick et al. · Nature · 1984 · 2.8K citations

Tumor Biology, Carcinoma Cells, Medicine +9

Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences

Julian Downward, Yosef Yarden, E. L. V. Mayes et al. · Nature · 1984 · 2.5K citations · Full text

Developmental Biology, Signal Transduction, Signaling Pathway +7

Phosphatidylinositol-3-OH kinase direct target of Ras

Pablo Rodriguez‐Viciana, Patricia H. Warne, Ritu Dhand et al. · Nature · 1994 · 1.9K citations

Signal Transduction, Signaling Pathway, Receptor Tyrosine Kinase +5

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB

Andrea Kauffmann-Zeh, Pablo Rodriguez‐Viciana, Eugen Ulrich et al. · Nature · 1997 · 1.2K citations

Signal Transduction, Signaling Pathway, Cell Regulation +9