Asim Khwaja

Role of Phosphoinositide 3-OH Kinase in Cell Transformation and Control of the Actin Cytoskeleton by Ras

Pablo Rodriguez‐Viciana, Patricia H. Warne, Asim Khwaja et al. · Cell · 1997 · 1.1K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Matrix adhesion and Ras transformation both activate a phosphoinositide 3‐OH kinase and protein kinase B/Akt cellular survival pathway

Asim Khwaja, Pablo Rodriguez‐Viciana, Stefan Wennström et al. · The EMBO Journal · 1997 · 1K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Arsenic trioxide and all-trans retinoic acid treatment for acute promyelocytic leukaemia in all risk groups (AML17): results of a randomised, controlled, phase 3 trial

Alan K. Burnett, Nigel H. Russell, Robert K. Hills et al. · The Lancet Oncology · 2015 · 543 citations

Medicine, Hematology, Oncology +8

The PI3 kinase, p38 SAP kinase, and NF-κB signal transduction pathways are involved in the survival and maturation of lipopolysaccharide-stimulated human monocyte–derived dendritic cells

Kirit M. Ardeshna, Arnold Pizzey, Stephen Devereux et al. · Blood · 2000 · 427 citations

Life Sciences, Cell Biology, Immunology +16

PI3-kinase/Akt is constitutively active in primary acute myeloid leukaemia cells and regulates survival and chemoresistance via NF-kB, MAPkinase and p53 pathways

Victoria Grandage, Rosemary E. Gale, David C. Linch et al. · Leukemia · 2005 · 282 citations

Medicine, Cell Biology, Oncology +13