In vivo receptor occupancy of mGlu5 receptor antagonists using the novel radioligand [3H]3-methoxy-5-(pyridin-2-ylethynyl)pyridine)

Distribution of metabotropic glutamate receptor mGluR5 immunoreactivity in rat brain

Carmelo Romano, Michael A. Sesma, Colin T. McDonald et al. · The Journal of Comparative Neurology · 1995 · 671 citations

Mice Lacking Metabotropic Glutamate Receptor 5 Show Impaired Learning and Reduced CA1 Long-Term Potentiation (LTP) But Normal CA3 LTP

Youming Lu, Zhengping Jia, Christopher Janus et al. · Journal of Neuroscience · 1997 · 630 citations · Full text

Immunohistochemical localization of a metabotropic glutamate receptor, mGluR5, in the rat brain

Ryuichi Shigemoto, Sakashi Nomura, Hitoshi Ohishi et al. · Neuroscience Letters · 1993 · 519 citations

Immunohistochemical Localization, Neurophysiology, Neuroanatomy +14

Potential anxiolytic‐ and antidepressant‐like effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist

E Tatarczyńska, Aleksandra Kłodzińska, E Chojnacka-Wójcik et al. · British Journal of Pharmacology · 2001 · 308 citations · Full text

Anxiolytic-Like Effects of the Prototypical Metabotropic Glutamate Receptor 5 Antagonist 2-Methyl-6-(phenylethynyl)pyridine in Rodents

Will Spooren, A. Vassout, H.C. Neijt et al. · Journal of Pharmacology and Experimental Therapeutics · 2000 · 266 citations