In vivo receptor occupancy of mGlu5 receptor antagonists using the novel radioligand [3H]3-methoxy-5-(pyridin-2-ylethynyl)pyridine)

References

Page 1

	Year	Citations
Distribution of metabotropic glutamate receptor mGluR5 immunoreactivity in rat brain Carmelo Romano, Michael A. Sesma, Colin T. McDonald, The Journal of Comparative Neurology	1995	671
Mice Lacking Metabotropic Glutamate Receptor 5 Show Impaired Learning and Reduced CA1 Long-Term Potentiation (LTP) But Normal CA3 LTP Youming Lu, Zhengping Jia, Christopher Janus, Journal of Neuroscience	1997	630
Immunohistochemical localization of a metabotropic glutamate receptor, mGluR5, in the rat brain Ryuichi Shigemoto, Sakashi Nomura, Hitoshi Ohishi, Neuroscience Letters Immunohistochemical LocalizationNeurophysiologyNeuroanatomyMedicineNeurotransmitter	1993	519
Potential anxiolytic‐ and antidepressant‐like effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist E Tatarczyńska, Aleksandra Kłodzińska, E Chojnacka-Wójcik, British Journal of Pharmacology	2001	308
Anxiolytic-Like Effects of the Prototypical Metabotropic Glutamate Receptor 5 Antagonist 2-Methyl-6-(phenylethynyl)pyridine in Rodents Will Spooren, A. Vassout, H.C. Neijt, Journal of Pharmacology and Experimental Therapeutics	2000	266
Chronic But Not Acute Treatment with a Metabotropic Glutamate 5 Receptor Antagonist Reverses the Akinetic Deficits in a Rat Model of Parkinsonism Nathalie Breysse, Christelle Baunez, Will Spooren, Journal of Neuroscience	2002	177
Metabotropic glutamate receptor subtype 5 (mGlu5) and nociceptive function Katherine Walker, M. Bowes, Moh Panesar, Neuropharmacology Pain MedicineMedicineNeuropathic PainMolecular PainNeuropharmacology	2001	165
Anticonvulsant activity of two metabotropic glutamate Group I antagonists selective for the mGlu5 receptor: 2-methyl-6-(phenylethynyl)-pyridine (MPEP), and (E)-6-methyl-2-styryl-pyridine (SIB 1893) Astrid G. Chapman, Karl Nanan, Martin W. Williams, Neuropharmacology NeurophysiologyMedicineFunctional SelectivitySib 1893Neuropeptide Receptor	2000	146
[3H]-Methoxymethyl-MTEP and [3H]-Methoxy-PEPy: potent and selective radioligands for the metabotropic glutamate subtype 5 (mGlu5) receptor Nicholas D. P. Cosford, Jeffrey Roppe, Lida Tehrani, Bioorganic & Medicinal Chemistry Letters BiochemistryG Protein-coupled ReceptorMedicineFunctional SelectivityMechanism Of Action	2003	146
Anxiolytic-like activity of the mGluR5 antagonist MPEPA comparison with diazepam and buspirone Jesse Brodkin, Chris S Busse, Stacey J. Sukoff Rizzo, Pharmacology Biochemistry and Behavior Anxiolytic-like ActivityMedicinePsychotropic MedicationMechanism Of ActionNeuropharmacology	2002	144

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