Mark A. Varney

2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist

F. Gasparini, Kurt Lingenhöhl, Natacha Stoehr et al. · Neuropharmacology · 1999 · 720 citations

Biochemistry, Functional Selectivity, Medicine +7

Effects of ketamine and n-methyl-d-aspartate on glutamate and dopamine release in the rat prefrontal cortex: modulation by a group II selective metabotropic glutamate receptor agonist LY379268

Daniel S. Lorrain, Christopher Baccei, Linda J. Bristow et al. · Neuroscience · 2003 · 429 citations

Psychiatry, Neurophysiology, Neurotransmitter +9

3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]- pyridine:  A Potent and Highly Selective Metabotropic Glutamate Subtype 5 Receptor Antagonist with Anxiolytic Activity

Nicholas D. P. Cosford, Lida Tehrani, Jeffrey Roppe et al. · Journal of Medicinal Chemistry · 2002 · 400 citations · Full text

Receptor Antagonist, Psychopharmacology, Pharmacotherapy +17

Differential distribution of voltage‐gated calcium channel alpha‐2 delta (α₂δ) subunit mRNA‐containing cells in the rat central nervous system and the dorsal root ganglia

Rebecca L. Cole, Sandra Lechner, Mark E. Williams et al. · The Journal of Comparative Neurology · 2005 · 223 citations

Synaptic Transmission, Neurotransmitter, Neurotransmission +22

SIB-1757 and SIB-1893: Selective, Noncompetitive Antagonists of Metabotropic Glutamate Receptor Type 5

Mark A. Varney, Nicholas D. P. Cosford, Christine Jachec et al. · Journal of Pharmacology and Experimental Therapeutics · 1999 · 189 citations