Concepedia

Nicholas D. P. Cosford

ND

89

Publications

5.7K

Citations

42

H-Index

1987

Active since

Affiliations

Sanford Burnham Prebys Medical Discovery Institute(Current)

Discovery Institute

General Atomics (United States)

Merck & Co., Inc., Rahway, NJ, USA (United States)

University of California San Diego

Nicholas D. P. Cosford is an author at Sanford Burnham Prebys Medical Discovery Institute specializing in medicine, pharmacology, and drug discovery.

ORCID

Top concepts

Publications per year

1987–2023

89

Publications

89

Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates

Daniel F. Egan, Matthew G. H. Chun, Mitchell Vamos et al. · Molecular Cell · 2015 · 704 citations · Full text

, , +12

3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]- pyridine:  A Potent and Highly Selective Metabotropic Glutamate Subtype 5 Receptor Antagonist with Anxiolytic Activity

Nicholas D. P. Cosford, Lida Tehrani, Jeffrey Roppe et al. · Journal of Medicinal Chemistry · 2002 · 400 citations · Full text

, , +17

SIB-1757 and SIB-1893: Selective, Noncompetitive Antagonists of Metabotropic Glutamate Receptor Type 5

Mark A. Varney, Nicholas D. P. Cosford, Christine Jachec et al. · Journal of Pharmacology and Experimental Therapeutics · 1999 · 189 citations

The Behavioral Profile of the Potent and Selective mGlu5 Receptor Antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine (MTEP) in Rodent Models of Anxiety

Chris S Busse, Jesse Brodkin, David Tattersall et al. · Neuropsychopharmacology · 2004 · 157 citations · Full text

, , +11

Synthesis, characterization, and first successful monkey imaging studies of metabotropic glutamate receptor subtype 5 (mGluR5) PET radiotracers

Terence G. Hamill, Stephen M. Krause, Christine Ryan et al. · Synapse · 2005 · 152 citations

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