Publication | Open Access

Discovery, synthesis, and structure–activity relationships of 2-aminoquinazoline derivatives as a novel class of metabotropic glutamate receptor 5 negative allosteric modulators

Negative Allosteric ModulatorsMolecular PharmacologyBiochemistryFunctional SelectivityMedicineMechanism Of ActionNeuropharmacology2-Aminoquinazoline DerivativesStructure–activity RelationshipsPharmacologyPharmaceutical ChemistryDrug Discovery