Concepedia

N-glycosylation of human nicastrin is required for interaction with the lectins from the secretory pathway calnexin and ERGIC-53

Vanessa A. Morais, Catarina Brito, Donald S. Pijak, Adam Crystal, Ryan R. Fortna, Tong Li, Phil Wong, Robert W. Doms, Júlia Costa

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2006 · 25 citations · 34 references

DOI

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References

34

β-Secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACE

Robert Vassar, Brian D. Bennett, Safura Babu‐Khan et al. · Science · 1999 · 3.8K citations · Full text

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Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and γ-secretase activity

Michael S. Wolfe, Weiming Xia, Beth L. Ostaszewski et al. · Nature · 1999 · 1.9K citations

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Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and βAPP processing

Gang Yu, Masaki Nishimura, Shigeki Arawaka et al. · Nature · 2000 · 904 citations

, , +10

Reconstitution of γ-secretase activity

Dieter Edbauer, Edith Winkler, Jörg T. Regula et al. · Nature Cell Biology · 2003 · 875 citations

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Photoactivated γ-secretase inhibitors directed to the active site covalently label presenilin 1

Yue‐Ming Li, Min Xu, Ming‐Tain Lai et al. · Nature · 2000 · 869 citations

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