Concepedia

Notch1 Regulates Maturation of CD4+ and CD8+ Thymocytes by Modulating TCR Signal Strength

David J. Izon, Jennifer A. Punt, Lanwei Xu, Fredrick G. Karnell, David Allman, Peggy Myung, Nancy J. Boerth, John C. Pui, Gary A. Koretzky, Warren S. Pear

Immunity · 2001 · 186 citations · 56 references

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References

56

Production of high-titer helper-free retroviruses by transient transfection.

Warren S. Pear, Garry P. Nolan, Martin Scott et al. · Proceedings of the National Academy of Sciences · 1993 · 2.3K citations

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A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain

Bart De Strooper, Wim Annaert, Philippe Cupers et al. · Nature · 1999 · 2.1K citations

, , +12

TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

Leif W. Ellisen, Daniel C. West, A. Lee Soreng et al. · Cell · 1991 · 1.7K citations

, , +14

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

Eric H. Schroeter, Jeffrey A. Kisslinger, Raphael Kopan · Nature · 1998 · 1.6K citations

, , +13

Signalling downstream of activated mammalian Notch

Sophie Jarriault, Christel Brou, Frédérique Logeat et al. · Nature · 1995 · 1.4K citations

, , +9