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Noncovalent tripeptidic thrombin inhibitors incorporating amidrazone, amine and amidine functions at P1

Koo Lee, Won‐Hyuk Jung, Cheol Won Park, Hee Dong Park, Sun Hwa Lee, Oh-Seok Kwon

Bioorganic & Medicinal Chemistry Letters · 2002 · 20 citations · 11 references

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11

The Importance of Enzyme Inhibition Kinetics for the Effect of Thrombin Inhibitors in a Rat Model of Arterial Thrombosis

Margareta Elg, David Gustafsson, Johanna Deinum · Thrombosis and Haemostasis · 1997 · 114 citations

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A Versatile Synthesis of Amidines from Nitriles<i>Via</i>Amidoximes

Brian D. Judkins, D. G. Allen, Tracey A. Cook et al. · Synthetic Communications · 1996 · 103 citations

, , +10

Antithrombotic Effect of Two Low Molecular Weight Thrombin Inhibitors and a Low-Molecular Weight Heparin in a Caval Vein Thrombosis Model in the Rat

Bengt I. Eriksson, Stefan Carlsson, Margit Halvarsson et al. · Thrombosis and Haemostasis · 1997 · 71 citations

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Discovery of a Novel, Selective, and Orally Bioavailable Class of Thrombin Inhibitors Incorporating Aminopyridyl Moieties at the P1 Position

Dong-Mei Feng, Stephen J. Gardell, Sidney D. Lewis et al. · Journal of Medicinal Chemistry · 1997 · 57 citations · Full text

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Design and Structure−Activity Relationships of Potent and Selective Inhibitors of Blood Coagulation Factor Xa

William R. Ewing, Michael R. Becker, Vincent E. Manetta et al. · Journal of Medicinal Chemistry · 1999 · 42 citations · Full text

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