Michael R. Becker

Crystal Structures of Human Factor Xa Complexed with Potent Inhibitors

S. Maignan, J.P. Guilloteau, Stéphanie Pouzieux et al. · Journal of Medicinal Chemistry · 2000 · 139 citations · Full text

X-ray Crystallography, Crystal Structure, Protein Assembly +21

Molecular Structures of Human Factor Xa Complexed with Ketopiperazine Inhibitors:  Preference for a Neutral Group in the S1 Pocket

S. Maignan, J.P. Guilloteau, Yong Mi Choi-Sledeski et al. · Journal of Medicinal Chemistry · 2003 · 118 citations · Full text

Pharmaceutical Science, Drug Target, Molecular Biology +19

Discovery of an Orally Efficacious Inhibitor of Coagulation Factor Xa Which Incorporates a Neutral P₁Ligand

Yong Mi Choi-Sledeski, Robert E. Kearney, Gregory Poli et al. · Journal of Medicinal Chemistry · 2003 · 78 citations · Full text

Orally Efficacious Inhibitor, Pharmaceutical Science, Pharmacotherapy +18

Total synthesis of (-)-denticulatins A and B: marine polypropionates from Siphonaria denticulata

Frederick E. Ziegler, Michael R. Becker · The Journal of Organic Chemistry · 1990 · 44 citations

Marine Biotechnology, Biosynthesis, Engineering +13

Design and Structure−Activity Relationships of Potent and Selective Inhibitors of Blood Coagulation Factor Xa

William R. Ewing, Michael R. Becker, Vincent E. Manetta et al. · Journal of Medicinal Chemistry · 1999 · 42 citations · Full text

Selective Inhibitors, Pharmacotherapy, Chemical Biology +19