Gregory Poli

Discovery of an Orally Efficacious Inhibitor of Coagulation Factor Xa Which Incorporates a Neutral P₁Ligand

Yong Mi Choi-Sledeski, Robert E. Kearney, Gregory Poli et al. · Journal of Medicinal Chemistry · 2003 · 78 citations · Full text

Orally Efficacious Inhibitor, Pharmaceutical Science, Pharmacotherapy +18

Quaternary substituted PDE4 inhibitors I: The synthesis and in vitro evaluation of a novel series of oxindoles

Christopher Hulme, Gregory Poli, Fu‐Chih Huang et al. · Bioorganic & Medicinal Chemistry Letters · 1998 · 20 citations · Full text

Pde4 Inhibitors, Combinatorial Chemistry, Medicinal Chemistry +11

Development of a novel series of (2-quinolinylmethoxy)phenyl-containing compounds as high-affinity leukotriene D4 receptor antagonists. 4. Addition of chromone moiety enhances leukotriene D4 receptor binding affinity

Fu Chih Huang, Robert A. Galemmo, Gregory Poli et al. · Journal of Medicinal Chemistry · 1991 · 16 citations · Full text

Development of a novel series of (2-quinolinylmethoxy)phenyl-containing compounds as high-affinity leukotriene D4 receptor antagonists. 2. Effects of an additional phenyl ring on receptor affinity

Fu Chih Huang, Robert A. Galemmo, William H. Johnson et al. · Journal of Medicinal Chemistry · 1990 · 15 citations · Full text

Pharmaceutical Science, Phenyl-containing Compounds, Pharmacotherapy +16

A β-tryptase inhibitor with a tropanylamide scaffold to improve in vitro stability and to lower hERG channel binding affinity

Guyan Liang, Yong Mi Choi-Sledeski, Patrick Shum et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 15 citations · Full text

Molecular Pharmacology, Molecular Physiology, Signal Transduction +9