Streamlined Syntheses of (−)-Dictyostatin, 16-Desmethyl-25,26-dihydrodictyostatin, and 6-<i>epi</i>-16-Desmethyl-25,26-dihydrodictyostatin

Wei Zhu, M. J. Jiménez, Won‐Hyuk Jung, +5

Journal of the American Chemical Society

Catalytic asymmetric allylation of aldehydes with BINOL-Ti(IV) complex accelerated by i-PrSSiMe3

Chan‐Mo Yu, Ha‐Soon Choi, Won‐Hyuk Jung, +1

Tetrahedron Letters

Chemical EngineeringCross-coupling ReactionEngineeringCatalytic Asymmetric AllylationOrganometallic Catalysis +4

Confirmation of the Stereostructure of (+)‐Cytostatin by Fluorous Mixture Synthesis of Four Candidate Stereoisomers

Won‐Hyuk Jung, Sabrina Guyenne, Concepción Riesco‐Fagundo, +3

Angewandte Chemie International Edition

Bioorganic ChemistryEngineeringMolecular BiologyOrganic ChemistryRelated Candidate Isomers +18

Effects of Subjoin Lewis Acid on the Catalytic Asymmetric Allylic Transfer Reactions of Aldehydes Promoted by BINOL-Ti(IV) Complex

Chan‐Mo Yu, Ha‐Soon Choi, Sook-Kyung Yoon, +1

Synlett

Chemical EngineeringCross-coupling ReactionEngineeringAldehydes PromotedAchiral Aldehydes +10

Efficacious and Orally Bioavailable Thrombin Inhibitors Based on a 2,5-Thienylamidine at the P1 Position:  Discovery of<i>N</i>-Carboxymethyl-<scp>d</scp>-diphenylalanyl-<scp>l</scp>-prolyl[(5-amidino-2-thienyl)methyl]amide

Koo Lee, Cheol Won Park, Won‐Hyuk Jung, +11

Journal of Medicinal Chemistry

Pharmaceutical SciencePharmacotherapyChemical BiologyPharmaceutical ChemistryThrombosis +17

Benzylamine-based selective and orally bioavailable inhibitors of thrombin

Koo Lee, Won‐Hyuk Jung, Cheol Won Park, +10

Bioorganic & Medicinal Chemistry Letters

ThrombosisMedicinal ChemistryBenzylamine-based SelectiveMedicinePharmacotherapy +4

Improved Synthesis of 6-<i>epi</i>-Dictyostatin and Antitumor Efficacy in Mice Bearing MDA-MB231 Human Breast Cancer Xenografts

Julie L. Eiseman, Lihua Bai, Won‐Hyuk Jung, +3

Journal of Medicinal Chemistry

Tumor BiologyMedicinal ChemistryBreast OncologyActive EpimersMedicine +13

Dictyostatin Flexibility Bridges Conformations in Solution and in the β-Tubulin Taxane Binding Site

Ashutosh S. Jogalekar, Krishnan Damodaran, Frederik H. Kriel, +5

Journal of the American Chemical Society

Noncovalent tripeptidic thrombin inhibitors incorporating amidrazone, amine and amidine functions at P1

Koo Lee, Won‐Hyuk Jung, Cheol Won Park, +3

Bioorganic & Medicinal Chemistry Letters

ThrombosisMedicinal ChemistryBiochemistryMedicineNatural Sciences +7

Bifunctional molecular accelerator for catalytic asymmetric allylation: R2MSR′ (M = B, Al) as a useful synergetic reagent

Chan‐Mo Yu, Ha‐Soon Choi, Won‐Hyuk Jung, +2

Chemical Communications

EngineeringOrganic ChemistryW. JungChemistrySpectra-structure Correlation +15