Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis

Regulatory T Cell Clones Induced by Oral Tolerance: Suppression of Autoimmune Encephalomyelitis

Youhai Chen, Vijay K. Kuchroo, Jun-ichi Inobe et al. · Science · 1994 · 2K citations

Encephalitogenic potential of the myelin basic protein peptide (amino acids 83–99) in multiple sclerosis: Results of a phase II clinical trial with an altered peptide ligand

Bibiana Bielekova, Bonnie L. Goodwin, Nancy Richert et al. · Nature Medicine · 2000 · 819 citations

Neurodegenerative Diseases, Encephalitogenic Potential, Neurobiology Of Disease +14

Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR–induced stop signal

Brian T. Fife, Kristen E. Pauken, Todd N. Eagar et al. · Nature Immunology · 2009 · 733 citations · Full text

Signal Transduction, Medicine, Immunology +5

A Single Course of Anti-CD3 Monoclonal Antibody hOKT3γ1(Ala-Ala) Results in Improvement in C-Peptide Responses and Clinical Parameters for at Least 2 Years after Onset of Type 1 Diabetes

Kevan C. Herold, Stephen E. Gitelman, Umesh Masharani et al. · Diabetes · 2005 · 631 citations · Full text

CNS myeloid DCs presenting endogenous myelin peptides 'preferentially' polarize CD4+ TH-17 cells in relapsing EAE

Samantha L. Bailey, Bettina Schreiner, Eileen McMahon et al. · Nature Immunology · 2007 · 451 citations

Autoimmune Disease, Endogenous Myelin Peptides, Medicine +8