Concepedia

Encephalitogenic potential of the myelin basic protein peptide (amino acids 83–99) in multiple sclerosis: Results of a phase II clinical trial with an altered peptide ligand

Bibiana Bielekova, Bonnie L. Goodwin, Nancy Richert, Irene Cortese, Takayuki Kondo, Ghazaleh Afshar, Bruno Gran, J.K. Eaton, Jack P. Antel, Joseph A. Frank,

Nature Medicine · 2000 · 826 citations · 42 references

DOI

Concepts

References

42

Rating neurologic impairment in multiple sclerosis

John F. Kurtzke · Neurology · 1983 · 14.9K citations

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Axonal Transection in the Lesions of Multiple Sclerosis

Bruce D. Trapp, John W. Peterson, Richard M. Ransohoff et al. · New England Journal of Medicine · 1998 · 4K citations · Full text

, , +17

General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acids.

Richard A. Houghten · Proceedings of the National Academy of Sciences · 1985 · 1.7K citations · Full text

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PROBLEMS OF EXPERIMENTAL TRIALS OF THERAPY IN MULTIPLE SCLEROSIS: REPORT BY THE PANEL ON THE EVALUATION OF EXPERIMENTAL TRIALS OF THERAPY IN MULTIPLE SCLEROSIS

George A. Schumacher, Gilbert W. Beebe, Robert F. Kibler et al. · Annals of the New York Academy of Sciences · 1965 · 1.4K citations

, , +10

Amino Acid Homology Between the Encephalitogenic Site of Myelin Basic Protein and Virus: Mechanism for Autoimmunity

Robert S. Fujinami, Michael B. A. Oldstone · Science · 1985 · 949 citations

, , +16