Bruno Gran

Encephalitogenic potential of the myelin basic protein peptide (amino acids 83–99) in multiple sclerosis: Results of a phase II clinical trial with an altered peptide ligand

Bibiana Bielekova, Bonnie L. Goodwin, Nancy Richert et al. · Nature Medicine · 2000 · 819 citations

Neurodegenerative Diseases, Encephalitogenic Potential, Neurobiology Of Disease +14

Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27–stimulated T cells

Denise Fitzgerald, Guang‐Xian Zhang, Mohamed El Behi et al. · Nature Immunology · 2007 · 527 citations

Immunology, Immune Regulation, Interleukin 27–Stimulated +20

IL-12p35-Deficient Mice Are Susceptible to Experimental Autoimmune Encephalomyelitis: Evidence for Redundancy in the IL-12 System in the Induction of Central Nervous System Autoimmune Demyelination

Bruno Gran, Guang‐Xian Zhang, Shuo Yu et al. · The Journal of Immunology · 2002 · 395 citations

IDO Upregulates Regulatory T Cells via Tryptophan Catabolite and Suppresses Encephalitogenic T Cell Responses in Experimental Autoimmune Encephalomyelitis

Yaping Yan, Guang-Xian Zhang, Bruno Gran et al. · The Journal of Immunology · 2010 · 347 citations · Full text

Effect of natalizumab on disease progression in secondary progressive multiple sclerosis (ASCEND): a phase 3, randomised, double-blind, placebo-controlled trial with an open-label extension

Raju Kapoor, Pei‐Ran Ho, Nolan Campbell et al. · The Lancet Neurology · 2018 · 327 citations · Full text

Disease Progression, Neurological Disorder, Immunology +8