Regulatory T cells promote myelin regeneration in the central nervous system

Yvonne Dombrowski, Thomas O’Hagan, Marie Dittmer, +22

Nature Neuroscience

Myelin RegenerationNeuroregenerationMedicineT-regulatory CellRegulatory T Cells +11

Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27–stimulated T cells

Denise Fitzgerald, Guang‐Xian Zhang, Mohamed El Behi, +7

Nature Immunology

ImmunologyImmune RegulationInterleukin 27–StimulatedCd4 T Cell ResponsesT Cells +18

Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition

Emanuela Pasciuto, Oliver T. Burton, Carlos P. Roca, +24

Cell

Suppressive Effect of IL-27 on Encephalitogenic Th17 Cells and the Effector Phase of Experimental Autoimmune Encephalomyelitis

Denise Fitzgerald, Bogoljub Ćirić, Tarik Touil, +6

The Journal of Immunology

Effector PhaseT-regulatory CellImmunologyImmune RegulationImmunologic Mechanism +27

Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and remyelination

Muktha S. Natrajan, Alerie Guzman de la Fuente, Abbe Crawford, +8

Brain

InflammationRetinaImmune DysregulationImmune Cell DevelopmentMedicine +13

Oral Resveratrol Reduces Neuronal Damage in a Model of Multiple Sclerosis

Kenneth S. Shindler, Elvira Ventura, Mahasweta Dutt, +3

Journal of Neuro-Ophthalmology

Adult neural stem cells expressing IL-10 confer potent immunomodulation and remyelination in experimental autoimmune encephalitis

Jingxian Yang, Zhilong Jiang, Denise Fitzgerald, +9

Journal of Clinical Investigation

ImmunologySocial SciencesExperimental Autoimmune EncephalitisInflammationNeuroinflammation +17

Targeting Siglecs with a sialic acid–decorated nanoparticle abrogates inflammation

Shaun Spence, Michelle K. Greene, François Fay, +19

Science Translational Medicine

Aging impairs peritoneal but not bone marrow‐derived macrophage phagocytosis

Eimear Linehan, Yvonne Dombrowski, Rachel Snoddy, +3

Aging Cell

InflammationMacrophage BiologyAutoimmune DiseaseImpaired PhagocytosisGranulocyte +13

Functional interleukin-17 receptor A is expressed in central nervous system glia and upregulated in experimental autoimmune encephalomyelitis

Jayasri Das Sarma, Bogoljub Ćirić, Ryan Marek, +6

Journal of Neuroinflammation