Concepedia

High-throughput screening methodology for the directed evolution of glycosyltransferases

Amir Aharoni, K. Thieme, Cecilia Chiu, Sabrina Buchini, Luke L. Lairson, Hongming Chen, N.C.J. Strynadka, Warren W. Wakarchuk, Stephen G. Withers

Nature Methods · 2006 · 235 citations · 13 references

DOI

Concepts

References

13

Directed evolution of an extremely fast phosphotriesterase by in vitro compartmentalization

Andrew D. Griffiths · The EMBO Journal · 2002 · 320 citations · Full text

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High-Throughput Screening of Enzyme Libraries: Thiolactonases Evolved by Fluorescence-Activated Sorting of Single Cells in Emulsion Compartments

Amir Aharoni, Gil Amitai, Shlomo Magdassi et al. · Chemistry & Biology · 2005 · 228 citations · Full text

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High-Throughput Screening of Enzyme Libraries: In Vitro Evolution of a β-Galactosidase by Fluorescence-Activated Sorting of Double Emulsions

Enrico Mastrobattista, Valérie Taly, Estelle Chanudet et al. · Chemistry & Biology · 2005 · 224 citations · Full text

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Structural analysis of the sialyltransferase CstII from Campylobacter jejuni in complex with a substrate analog

Cecilia Chiu, Andrew G. Watts, Luke L. Lairson et al. · Nature Structural & Molecular Biology · 2004 · 221 citations

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Engineering of protease variants exhibiting high catalytic activity and exquisite substrate selectivity

Navin Varadarajan, Jongsik Gam, Mark Olsen et al. · Proceedings of the National Academy of Sciences · 2005 · 164 citations

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