Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion

Rui Su, Lei Dong, Yangchan Li, +36

Cancer Cell

Immune EvasionMedicineStem Cell MobilizationImmunologyStem Cell Research +6

Antibody affinity maturation using bacterial surface display

Patrick S. Daugherty, G. Chen, Mark Olsen, +2

Protein Engineering Design and Selection

Flow CytometryImmunocytochemical TechniqueQuantitative SystemNatural SciencesBioanalysis +12

Function-based isolation of novel enzymes from a large library

Mark Olsen, Daren Stephens, Devin Griffiths, +3

Nature Biotechnology

BiosynthesisEngineeringCellular EnzymologyBiochemistryNatural Sciences +5

Engineering of protease variants exhibiting high catalytic activity and exquisite substrate selectivity

Navin Varadarajan, Jongsik Gam, Mark Olsen, +2

Proceedings of the National Academy of Sciences

Identification of the Epitope for the Epidermal Growth Factor Receptor-specific Monoclonal Antibody 806 Reveals That It Preferentially Recognizes an Untethered Form of the Receptor

Terrance G. Johns, Timothy E. Adams, Jennifer R. Cochran, +14

Journal of Biological Chemistry

Important Role of FTO in the Survival of Rare Panresistant Triple-Negative Inflammatory Breast Cancer Cells Facing a Severe Metabolic Challenge

Balraj Singh, Hannah E. Kinne, Ryan D. Milligan, +3

PLoS ONE

Breast OncologySum149 CellsImmunologyCell DeathMetabolic Remodeling +18

Development of an optimized expression system for the screening of antibody libraries displayed on the Escherichia coli surface

Patrick S. Daugherty, Mark Olsen, Brent L. Iverson, +1

Protein Engineering Design and Selection

Synthesis of a FTO Inhibitor with Anticonvulsant Activity

Guanqun Zheng, Thomas C. Cox, Leah Tribbey, +9

ACS Chemical Neuroscience

Selection of Horseradish Peroxidase Variants with Enhanced Enantioselectivity by Yeast Surface Display

Daša Lipovšek, Eugene Antipov, Kathryn A. Armstrong, +4

Chemistry & Biology

BiosynthesisEngineeringBiochemistryEnhanced EnantioselectivityNatural Sciences +11

A cell-surface β-hydroxylase is a biomarker and therapeutic target for hepatocellular carcinoma

Arihiro Aihara, Chiung-Kuei Huang, Mark Olsen, +5

Hepatology