Luke L. Lairson

A regenerative approach to the treatment of multiple sclerosis

V. Deshmukh, Virginie Tardif, Costas A. Lyssiotis et al. · Nature · 2013 · 508 citations · Full text

Regenerative Medicine, Neuroregeneration, Neurological Disorder +8

Antitumor activity of a systemic STING-activating non-nucleotide cGAMP mimetic

Emily N. Chin, Chenguang Yu, Vincent F. Vartabedian et al. · Science · 2020 · 483 citations

Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4

Costas A. Lyssiotis, Ruth K. Foreman, Judith Staerk et al. · Proceedings of the National Academy of Sciences · 2009 · 363 citations · Full text

Regenerative Medicine, Small-molecule Screening Platform, Induced Pluripotent Stem Cell +13

An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells

Ekaterina V. Vinogradova, Xiaoyu Zhang, David Remillard et al. · Cell · 2020 · 352 citations · Full text

Electrophile-cysteine Interactions, Signal Transduction, Biochemistry +10

Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers

Edouard Mullarky, Natasha C. Lucki, Reza Beheshti Zavareh et al. · Proceedings of the National Academy of Sciences · 2016 · 331 citations · Full text

Engineering, Aldo-keto Reductase, Small Molecule Inhibitor +20