Concepedia

Inhibition of cathepsin K reduces cartilage degeneration in the anterior cruciate ligament transection rabbit and murine models of osteoarthritis

Tadashi Hayami, Ya Zhuo, Gregg Wesolowski, Maureen Pickarski, Le T. Duong

Bone · 2012 · 124 citations · 34 references

DOI

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References

34

Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice

Paul Säftig, Ernst B. Hunziker, Olaf Wehmeyer et al. · Proceedings of the National Academy of Sciences · 1998 · 910 citations

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Characterization of articular cartilage and subchondral bone changes in the rat anterior cruciate ligament transection and meniscectomized models of osteoarthritis

Tadashi Hayami, Maureen Pickarski, Ya Zhuo et al. · Bone · 2005 · 627 citations

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Osteoarthritis development in novel experimental mouse models induced by knee joint instability

Satoru Kamekura, Kazuto Hoshi, Takashi Shimoaka et al. · Osteoarthritis and Cartilage · 2005 · 599 citations · Full text

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The role of subchondral bone remodeling in osteoarthritis: Reduction of cartilage degeneration and prevention of osteophyte formation by alendronate in the rat anterior cruciate ligament transection model

Tadashi Hayami, Maureen Pickarski, Gregg Wesolowski et al. · Arthritis & Rheumatism · 2004 · 560 citations

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Cathepsin K Knockout Mice Develop Osteopetrosis Due to a Deficit in Matrix Degradation but Not Demineralization

Maxine Gowen, Francesca Lazner, Robert A. Dodds et al. · Journal of Bone and Mineral Research · 1999 · 489 citations · Full text

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