Concepedia

Bat3 promotes T cell responses and autoimmunity by repressing Tim-3–mediated cell death and exhaustion

Manu Rangachari, Chen Zhu, Kaori Sakuishi, Sheng Xiao, József Kármán, A. Chen, Mathieu Angin, Andrew Wakeham, Edward Greenfield, Raymond A. Sobel,

Nature Medicine · 2012 · 382 citations · 41 references

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41

Molecular Signature of CD8+ T Cell Exhaustion during Chronic Viral Infection

E. John Wherry, Sang‐Jun Ha, Susan M. Kaech et al. · Immunity · 2007 · 2.1K citations

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Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity

Kaori Sakuishi, Lionel Apétoh, Jenna M. Sullivan et al. · The Journal of Experimental Medicine · 2010 · 2.1K citations · Full text

, , +16

Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection

Shawn D. Blackburn, Haina Shin, W. Nicholas Haining et al. · Nature Immunology · 2008 · 2.1K citations · Full text

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The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity

Chen Zhu, Ana C. Anderson, Anna Schubart et al. · Nature Immunology · 2005 · 2K citations

, , +13

Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease

Laurent Monney, Catherine A. Sabatos, Jason L. Gaglia et al. · Nature · 2002 · 1.6K citations

, , +16