Concepedia

The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity

Chen Zhu, Ana C. Anderson, Anna Schubart, Huabao Xiong, Jaime Imitola, Samia J. Khoury, Xin Xiao Zheng, Terry B. Strom, Vijay K. Kuchroo

Nature Immunology · 2005 · 2K citations · 23 references

DOI

Concepts

References

23

Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease

Laurent Monney, Catherine A. Sabatos, Jason L. Gaglia et al. · Nature · 2002 · 1.6K citations

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Mice with a disrupted IFN-γ gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE)

Iris Ferber, Stefan Brocke, Cariel Taylor-Edwards et al. · The Journal of Immunology · 1996 · 973 citations · Full text

, , +17

Tim-3 inhibits T helper type 1–mediated auto- and alloimmune responses and promotes immunological tolerance

Alberto Sánchez‐Fueyo, Jane Tian, Dominic Picarella et al. · Nature Immunology · 2003 · 701 citations

, , +16

Interaction of Tim-3 and Tim-3 ligand regulates T helper type 1 responses and induction of peripheral tolerance

Catherine A. Sabatos, Sumone Chakravarti, Anna Schubart et al. · Nature Immunology · 2003 · 619 citations

, , +16

Evidence that BCL-2 represses apoptosis by regulating endoplasmic reticulum-associated Ca2+ fluxes.

Mildred Lam, George Dubyak, Liang Chen et al. · Proceedings of the National Academy of Sciences · 1994 · 602 citations

, , +16