Raymond A. Sobel

B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy

Vijay K. Kuchroo, Mercy Prabhu Das, Julia A. Brown et al. · Cell · 1995 · 1.7K citations · Full text

Th1/th2 Developmental Pathways, Disease Therapy, Autoimmune Disease +11

Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease

Laurent Monney, Catherine A. Sabatos, Jason L. Gaglia et al. · Nature · 2002 · 1.6K citations

Inflammation, Autoimmune Disease, Th1-specific Cell Surface +15

Induction and molecular signature of pathogenic TH17 cells

Youjin Lee, Amit Awasthi, Nir Yosef et al. · Nature Immunology · 2012 · 1.1K citations · Full text

Autoimmune Disease, T-regulatory Cell, Pathogenesis +6

The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease

Sawsan Youssef, Olaf Stüve, Juan C. Patarroyo et al. · Nature · 2002 · 1.1K citations

Inflammation, Autoimmune Disease, Disease Mechanism +13

IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ IL-10+ Foxp3− effector T cells

Valérie Dardalhon, Amit Awasthi, Hyoung Kwon et al. · Nature Immunology · 2008 · 1.1K citations · Full text

Cytokine, T-regulatory Cell, Immune Regulation +7