Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection

Shawn D. Blackburn, Haina Shin, W. Nicholas Haining, +7

Nature Immunology

Viral PersistenceImmunologyAntiviral ResponseVirologyAutoimmunity +5

A vaccine strategy that protects against genital herpes by establishing local memory T cells

Haina Shin, Akiko Iwasaki

Nature

VaccinationVaccine DevelopmentVaccine StrategyVaccine TargetImmunology +7

Selective expansion of a subset of exhausted CD8 T cells by αPD-L1 blockade

Shawn D. Blackburn, Haina Shin, Gordon J. Freeman, +1

Proceedings of the National Academy of Sciences

Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF

Michael Quigley, Florencia Pereyra, Björn Nilsson, +23

Nature Medicine

Transcriptional AnalysisHuman RetrovirusT-regulatory CellImmunologyAntiviral Response +7

A Role for the Transcriptional Repressor Blimp-1 in CD8+ T Cell Exhaustion during Chronic Viral Infection

Haina Shin, Shawn D. Blackburn, Andrew M. Intlekofer, +4

Immunity

Viral PersistencePathogenesisImmunologyAntiviral ResponseVirology +5

Anomalous Type 17 Response to Viral Infection by CD8 ⁺ T Cells Lacking T-bet and Eomesodermin

Andrew M. Intlekofer, Arnob Banerjee, Naofumi Takemoto, +7

Science

Viral antigen and extensive division maintain virus-specific CD8 T cells during chronic infection

Haina Shin, Shawn D. Blackburn, Joseph N. Blattman, +1

The Journal of Experimental Medicine

Tissue-Specific Differences in PD-1 and PD-L1 Expression during Chronic Viral Infection: Implications for CD8 T-Cell Exhaustion

Shawn D. Blackburn, Alison Crawford, Haina Shin, +3

Journal of Virology

Tissue-specific DifferencesPd-1/pd-l PathwayCd8 T-cell ExhaustionAutoimmune DiseasePd-l1 Expression +12

Bystander Chronic Infection Negatively Impacts Development of CD8+ T Cell Memory

Erietta Stelekati, Haina Shin, Travis A. Doering, +13

Immunity

Autoimmune DiseaseT-regulatory CellImmunologyBystander Chronic InfectionAutoimmunity +4

The effect of temperature on the activation of thymocytes by interleukins I and II.

D F Hanson, Patrick J. Murphy, R Silicano, +1

The Journal of Immunology

InflammationCytokineIl 1Autoimmune DiseaseImmunology +13