Concepedia

Histone deacetylase inhibitors cooperate with IFN-γ to restore caspase-8 expression and overcome TRAIL resistance in cancers with silencing of caspase-8

Sabine Häcker, Anna‐Maria Dittrich, Andrea Mohr, T. Schweitzer, Stefan Rutkowski, Simone Fulda

Oncogene · 2009 · 98 citations · 31 references

DOI

Concepts

References

31

Two CD95 (APO‐1/Fas) signaling pathways

Carsten Scaffidi · The EMBO Journal · 1998 · 3K citations · Full text

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Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells

Martin Göttlicher · The EMBO Journal · 2001 · 1.9K citations · Full text

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Targeted Disruption of the Mouse Caspase 8 Gene Ablates Cell Death Induction by the TNF Receptors, Fas/Apo1, and DR3 and Is Lethal Prenatally

Eugene Varfolomeev, Marcus Schuchmann, Victor Luria et al. · Immunity · 1998 · 1.2K citations · Full text

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Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

Tal Teitz, Tie Wei, Marcus B. Valentine et al. · Nature Medicine · 2000 · 804 citations

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The CD95 (APO-1/Fas) system mediates drug-induced apoptosis in neuroblastoma cells.

Simone Fulda, Hauke Sieverts, Claudia Friesen et al. · PubMed · 1997 · 450 citations

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