Histone deacetylase inhibitors cooperate with IFN-γ to restore caspase-8 expression and overcome TRAIL resistance in cancers with silencing of caspase-8

Sabine Häcker, Anna‐Maria Dittrich, Andrea Mohr, +4

Oncogene

MedicineHistone Deacetylase InhibitorsCancer Cell BiologyImmune Checkpoint InhibitorCancer Biology +8

Differential Induction of Apoptosis and Senescence by the DNA Methyltransferase Inhibitors 5-Azacytidine and 5-Aza-2′-Deoxycytidine in Solid Tumor Cells

Sascha Venturelli, Alexander Berger, Timo Weiland, +11

Molecular Cancer Therapeutics

ApoptosisCell DeathRational ChoiceCancer BiologyTumor Biology +16

CXorf61 is a target for T cell based immunotherapy of triple-negative breast cancer

Claudia Paret, Petra Simon, Kirsten Vormbrock, +12

Oncotarget

Histone deacetylase inhibitors sensitize glioblastoma cells to TRAIL-induced apoptosis by c-myc-mediated downregulation of cFLIP

Annette Bangert, Silvia Cristofanon, I Eckhardt, +7

Oncogene

GliomaMedicineApoptosisHistone Deacetylase InhibitorsCell Death +6

Identification of a novel pro‐apopotic function of NF‐κB in the DNA damage response

Sabine Karl, Yvonne Pritschow, Meta Volčič, +5

Journal of Cellular and Molecular Medicine

Dna DamageApoptosisCell DeathMolecular BiologyCancer Biology +17

Cytotoxic drug-induced, p53-mediated upregulation of caspase-8 in tumor cells

Harald Ehrhardt, Sabine Häcker, Sabine Wittmann, +5

Oncogene

MedicineApoptosisCell DeathTumor CellsCancer Biology +3

Differential Export Requirements for Shuttling Serine/Arginine-type mRNA-binding Proteins

Sabine Häcker, Heike Krebber

Journal of Biological Chemistry

Histone deacetylase inhibitors prime medulloblastoma cells for chemotherapy-induced apoptosis by enhancing p53-dependent Bax activation

Sabine Häcker, Sabine Karl, Ines Mader, +5

Oncogene

OncologyMedicineApoptosisCell DeathP53-dependent Bax Activation +6

Loss of Caspase-8 Expression Does Not Correlate with <i>MYCN</i> Amplification, Aggressive Disease, or Prognosis in Neuroblastoma

Simone Fulda, Christopher Poremba, Bernd Berwanger, +5

Cancer Research

Chemosensitization of glioblastoma cells by the histone deacetylase inhibitor MS275

Annette Bangert, Sabine Häcker, Silvia Cristofanon, +2

Anti-Cancer Drugs

Neuro-oncologyGliomaHistone Deacetylase InhibitorMedicinePharmacology +11