Nature Protocols · 2014 · 790 citations · 35 references
Life SciencesGeneticsMolecular GeneticsGenome EditingPlant BiotechnologyPlant GeneticsCrispr-based EngineeringCrispr-cas SystemsCrop GenomicsGuide Rna DesignPlant Genetic EngineeringPlant TransformationCrispr-based Genome EngineeringCrispr-cas Genome EditingCrispr-cas Systems In PlantsCrispr-cas9 Genome EditingGenome Editing In Crop Development
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A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity
Martin Jínek, Krzysztof Chylinski, Ines Fonfara et al. · Science · 2012 · 17.3K citations · Full text
Multiplex Genome Engineering Using CRISPR/Cas Systems
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Genome engineering using the CRISPR-Cas9 system
F. Ann Ran, Patrick D. Hsu, Jason Wright et al. · Nature Protocols · 2013 · 11.7K citations · Full text
RNA-Guided Human Genome Engineering via Cas9
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DNA targeting specificity of RNA-guided Cas9 nucleases
Patrick D. Hsu, David A. Scott, Joshua A. Weinstein et al. · Nature Biotechnology · 2013 · 4.9K citations · Full text