Concepedia

Rapid degradation of a large fraction of newly synthesized proteins by proteasomes

Ulrich S. Schubert, Luis C. Antón, James S. Gibbs, Christopher C. Norbury, Jonathan W. Yewdell, Jack R. Bennink

Nature · 2000 · 1.5K citations · 13 references

DOI

Concepts

References

13

Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

Akio Adachi, Howard E. Gendelman, Scott Koenig et al. · Journal of Virology · 1986 · 2.9K citations · Full text

, , +16

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

Kenneth L. Rock, Colette F. Gramm, Lisa Rothstein et al. · Cell · 1994 · 2.5K citations

, , +14

Aggresomes: A Cellular Response to Misfolded Proteins

Jennifer Johnston, Cristina L. Ward, Ron R. Kopito · The Journal of Cell Biology · 1998 · 2.2K citations · Full text

, , +17

Inhibition of Proteasome Activities and Subunit-Specific Amino-Terminal Threonine Modification by Lactacystin

Gabriel Fenteany, Robert F. Standaert, William S. Lane et al. · Science · 1995 · 1.6K citations

, , +15

Fundamental Immunology

P. C. Anderson · JAMA · 1999 · 1K citations

, , +6